BDBM50322009 3-(3,4-Dimethylphenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1173814

SMILES COc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(C)c(C)c1

InChI Key InChIKey=DHEZMKZYJNFVFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322009   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322009(3-(3,4-Dimethylphenyl)-5-(4-methoxyphenyl)-4,5-dih...)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of human recombinant HER-2 cytoplasmic domain (676 to 1245) autophosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322009(3-(3,4-Dimethylphenyl)-5-(4-methoxyphenyl)-4,5-dih...)
Affinity DataIC50: 70nMAssay Description:Inhibition of histidine-tagged recombinant EGFR autophosphorylation expressed in Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed