BDBM50321837 CHEMBL1173681::N-(isoquinolin-5-yl)-5-[4-(trifluoromethyl)phenyl]oxazol-2-amine

SMILES FC(F)(F)c1ccc(cc1)-c1cnc(Nc2cccc3cnccc23)o1

InChI Key InChIKey=HNEULCHPLQURLY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321837   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50321837(N-(isoquinolin-5-yl)-5-[4-(trifluoromethyl)phenyl]...)Copy SMILESCopy InChI

Affinity DataIC50: 229nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/31/2012
Entry Details Article
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