BDBM50321830 CHEMBL1173157::N1-{5-[4-(trifluoromethyl)phenyl]oxazol-2-yl}-5,6,7,8-tetrahydronaphthalene-1,7-diamine

SMILES NC1CCc2cccc(Nc3ncc(o3)-c3ccc(cc3)C(F)(F)F)c2C1

InChI Key InChIKey=CAZPUPYLGDBILQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321830   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50321830(N1-{5-[4-(trifluoromethyl)phenyl]oxazol-2-yl}-5,6,...)Copy SMILESCopy InChI

Affinity DataIC50: 327nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/31/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL