BDBM50321797 (S)-2-(1'-(3-phenylpropyl)spiro[isochroman-1,4'-piperidine]-3-yl)ethanol::CHEMBL1169963

SMILES OCC[C@@H]1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1

InChI Key InChIKey=TUFFDFRXRYJTGB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321797   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321797((S)-2-(1'-(3-phenylpropyl)spiro[isochroman-1,4'-pi...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321797((S)-2-(1'-(3-phenylpropyl)spiro[isochroman-1,4'-pi...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50321797((S)-2-(1'-(3-phenylpropyl)spiro[isochroman-1,4'-pi...)
Affinity DataKi:  519nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed