BDBM50321726 CHEMBL1172449::cyanopeptolin 1020

SMILES [#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6](-[#8-])=O)-[#6](=O)-[#7]-[#6]-1-[#6](-[#6])-[#8]-[#6](=O)-[#6](-[#7]-[#6](=O)-[#6](-[#6]-c2ccc(-[#8])cc2)-[#7](-[#6])-[#6](=O)-[#6](-[#6]-c2ccccc2)-[#7]-2-[#6](-[#8])-[#6]-[#6]-[#6](-[#7]-[#6](=O)-[#6](-[#6]-[#6]-[#6]\[#7+]=[#6](\[#7])-[#7])-[#7]-[#6]-1=O)-[#6]-2=O)-[#6](-[#6])-[#6]

InChI Key InChIKey=KFVBBPKAYRQLIL-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321726   

TargetCoagulation factor XI(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 490nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(cyanopeptolin 1020 | CHEMBL1172449)
Affinity DataIC50: 6.05E+5nMAssay Description:Inhibition of human LMW urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed