BDBM50321660 6-(1-benzyl-1H-pyrazol-4-yl)-3-phenylimidazo[1,2-a]pyrazine::CHEMBL1170532

SMILES C(c1ccccc1)n1cc(cn1)-c1cn2c(cnc2cn1)-c1ccccc1

InChI Key InChIKey=BNGJSLHOYAZWHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321660   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50321660(6-(1-benzyl-1H-pyrazol-4-yl)-3-phenylimidazo[1,2-a...)
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibition of CHK1 by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50321660(6-(1-benzyl-1H-pyrazol-4-yl)-3-phenylimidazo[1,2-a...)
Affinity DataIC50: 4.79E+6nMAssay Description:Inhibition of CHK1 (unknown origin) assessed as inhibition of CDC25 phosphorylation after 30 min by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article