BDBM50321642 1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-(2,2,2-trifluoroethoxy)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid::CHEMBL1169816

SMILES OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(c(F)s1)-c1ccc(F)c(OCC(F)(F)F)c1

InChI Key InChIKey=BDIGMKGQBFWVKX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321642   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50321642(1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-(2,2,2-trifl...)
Affinity DataEC50:  950nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed