BDBM50321633 1-(3-chloro-5-(5-ethyl-4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid::CHEMBL1171783

SMILES CCc1sc(NC(=O)c2cnc(N3CCC(CC3)C(O)=O)c(Cl)c2)nc1-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=NLJGONGPOFDMMI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321633   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50321633(1-(3-chloro-5-(5-ethyl-4-(4-fluoro-3-(trifluoromet...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed