BDBM50321542 CHEMBL1170137::N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-(methylsulfonamido)benzamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(NS(C)(=O)=O)cc3)sc12

InChI Key InChIKey=SVHRQWMVLCYEQP-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321542   

TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321542(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321542(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321542(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321542(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed