BDBM50321537 CHEMBL1170131::N-(7-(N-(2-(dimethylamino)-2-oxoethyl)acetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-fluorobenzamide

SMILES COc1ccc(N(CC(=O)N(C)C)C(C)=O)c2sc(NC(=O)c3ccc(F)cc3)nc12

InChI Key InChIKey=QONQGZZBFPEGKF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321537   

TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321537(N-(7-(N-(2-(dimethylamino)-2-oxoethyl)acetamido)-4...)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321537(N-(7-(N-(2-(dimethylamino)-2-oxoethyl)acetamido)-4...)
Affinity DataKi:  480nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321537(N-(7-(N-(2-(dimethylamino)-2-oxoethyl)acetamido)-4...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed