BDBM50321455 2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thiophene-3-sulfonamide::CHEMBL1172329

SMILES Cc1ccc(cc1)N(SC(Cl)(Cl)Cl)S(=O)(=O)c1cc(Cl)sc1Cl

InChI Key InChIKey=PKAHLRVRIDTYNC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321455   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human CDK7/Cyclin H/MAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50: 300nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed