BDBM50321446 4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide::CHEMBL1170012

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=LAQWXSZWFLYJOE-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50321446   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CDK7/Cyclin H/MAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataIC50: 700nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataEC50:  2.95E+4nMAssay Description:Agonist activity at human FFA4 receptor expressed in CHO-K1 cells assessed as increase in amplitude of dynamic mass redistribution response by DMR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50321446(4-methyl-N-(3-(trifluoromethyl)phenyl)benzenesulfo...)
Affinity DataEC50:  4.90E+4nMAssay Description:Agonist activity at human FFA1 receptor expressed in CHO-K1 cells assessed as increase in dynamic mass redistribution response by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed