BDBM50320964 3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide::CHEMBL1164957

SMILES Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2ncccc2c1

InChI Key InChIKey=CJTQBCMGMLTHPI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50320964   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 540nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 650nMAssay Description:Inhibition of PKCmuMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 940nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50320964(3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed