BDBM50320891 9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromide::CHEMBL1164137

SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OCCCOc1ccc(Cl)cc1

InChI Key InChIKey=JJPOWRAZNKDAPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320891   

TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 715nMAssay Description:Inhibition of electric eel AChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 7.74E+4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed