BDBM50320409 CHEMBL1084206::N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES COc1cccc(c1)N1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO

InChI Key InChIKey=RMMYIAVIROFVLC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320409   

TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 163nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 49nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed