BDBM50320404 CHEMBL1085748::N-hydroxy-4-(4-(4-(5-isopropyl-2-methoxyphenyl)piperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES COc1ccc(cc1C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO)C(C)C

InChI Key InChIKey=DNOKLXCRZPAPJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50320404   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320404(N-hydroxy-4-(4-(4-(5-isopropyl-2-methoxyphenyl)pip...)
Affinity DataIC50: 70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320404(N-hydroxy-4-(4-(4-(5-isopropyl-2-methoxyphenyl)pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed