BDBM50320401 CHEMBL1082371::N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperidin-1-yl)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES COc1ccc(C2CCN(CC2)c2ccc(cc2)S(=O)(=O)C2(CCOCC2)C(=O)NO)c(C)c1

InChI Key InChIKey=PYJCXRBSZSSHDD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320401   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperi...)
Affinity DataIC50: 505nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed