BDBM50320246 2,3,5-trichloro-4-(1-(1-cyclopropylethyl)-3-methyl-6-oxo-1,6-dihydro-1,2,4-triazin-5-ylamino)benzonitrile::CHEMBL1083343

SMILES CC(C1CC1)n1nc(C)nc(Nc2c(Cl)cc(C#N)c(Cl)c2Cl)c1=O

InChI Key InChIKey=YHYKEAJHBMENHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320246   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50320246(2,3,5-trichloro-4-(1-(1-cyclopropylethyl)-3-methyl...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]Tyr-ovine CRF from rat CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed