BDBM50320123 CHEMBL1082996::trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-3-methylbutanamide

SMILES CC(C)(CC(=O)N[C@H]1C[C@@H]1c1cccc(Cl)c1)CC(=O)N1C[C@@H](F)C[C@H]1C#C

InChI Key InChIKey=SJTHJFXLNKJCTG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50320123   

TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of DPP4 in presence of 50% rat serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50320123(trans-N-(2-(3-chlorophenyl)cyclopropyl)-3-(2-((S)-...)
Affinity DataIC50: 847nMAssay Description:Inhibition of DPP4 in presence of 50% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed