BDBM50319757 CHEMBL1085710::N-(3-(dimethylamino)propyl)-4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesulfonamide

SMILES CN(C)CCCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2ccsc2)cc1

InChI Key InChIKey=LPTGWJNQHKOQKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319757   

LigandPNGBDBM50319757(N-(3-(dimethylamino)propyl)-4-(4-(thiophen-3-yl)py...)
Affinity DataIC50: 170nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319757(N-(3-(dimethylamino)propyl)-4-(4-(thiophen-3-yl)py...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed