BDBM50319755 CHEMBL1085880::N-(2-(dimethylamino)ethyl)-4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesulfonamide

SMILES CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(n2)-c2ccsc2)cc1

InChI Key InChIKey=AUZFWDQAVYWVTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319755   

LigandPNGBDBM50319755(N-(2-(dimethylamino)ethyl)-4-(4-(thiophen-3-yl)pyr...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319755(N-(2-(dimethylamino)ethyl)-4-(4-(thiophen-3-yl)pyr...)
Affinity DataIC50: 770nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed