BDBM50319753 4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesulfonamide::CHEMBL1084970

SMILES NS(=O)(=O)c1ccc(Nc2nccc(n2)-c2ccsc2)cc1

InChI Key InChIKey=JUIXZPWSSOKEIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319753   

LigandPNGBDBM50319753(4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesul...)
Affinity DataIC50: 180nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319753(4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesul...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed