BDBM50319750 CHEMBL1083482::N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]quinazolin-8-yl)isobutyramide

SMILES CC(C)C(=O)Nc1ccc-2c(CCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1

InChI Key InChIKey=RWLKOGVBOMMSBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319750   

LigandPNGBDBM50319750(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319750(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed