BDBM50319748 3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]quinazolin-8-yl)but-2-enamide::CHEMBL1083175

SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1ccc-2c(-[#6]-[#6]-c3cnc(-[#7]-c4ccc(cc4)S([#7])(=O)=O)nc-23)c1

InChI Key InChIKey=GQQFPUBENTUSRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319748   

LigandPNGBDBM50319748(3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319748(3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 8.25E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed