BDBM50319743 CHEMBL1085122::N-(4-(2-(4-sulfamoylphenylamino)pyrimidin-4-yl)phenyl)-2-(thiophen-2-yl)acetamide

SMILES NS(=O)(=O)c1ccc(Nc2nccc(n2)-c2ccc(NC(=O)Cc3cccs3)cc2)cc1

InChI Key InChIKey=MZUCCTLUJWKQJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319743   

LigandPNGBDBM50319743(N-(4-(2-(4-sulfamoylphenylamino)pyrimidin-4-yl)phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319743(N-(4-(2-(4-sulfamoylphenylamino)pyrimidin-4-yl)phe...)
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed