BDBM50319600 2,2-Difluoro-3-[3-(2-fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylpropan-1-amine::CHEMBL1085830

SMILES CNCC(F)(F)CN1c2ccccc2N(c2ccccc2F)S1(=O)=O

InChI Key InChIKey=QWFUAOOOLIDWBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319600   

LigandPNGBDBM50319600(2,2-Difluoro-3-[3-(2-fluorophenyl)-2,2-dioxido-2,1...)
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319600(2,2-Difluoro-3-[3-(2-fluorophenyl)-2,2-dioxido-2,1...)
Affinity DataIC50: 238nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed