BDBM50319172 4-Ethoxycarbonylamino-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1083458

SMILES CCCc1nc(C)c2c(NC(=O)OCC)nc3ccc(OC)nc3n12

InChI Key InChIKey=PAJXSBMFHFVGLO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319172   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biotie Therapies

Curated by ChEMBL

LigandBDBM50319172(4-Ethoxycarbonylamino-8-methoxy-3-methyl-1-propyl-...)Copy SMILESCopy InChI

Affinity DataIC50: 206nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2010
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