BDBM50319169 3,4-Dimethoxy-1-isobutyl-8-methoxy-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1085406

SMILES COc1ccc2nc(C)c3c(C)nc(CC(C)C)n3c2n1

InChI Key InChIKey=HPEDPUYXSWYJIV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319169   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biotie Therapies

Curated by ChEMBL

LigandBDBM50319169(3,4-Dimethoxy-1-isobutyl-8-methoxy-imidazo[1,5-a]p...)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2010
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL