BDBM50319166 1-Propyl-3,4,8-trimethyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1086352

SMILES CCCc1nc(C)c2c(C)nc3ccc(C)nc3n12

InChI Key InChIKey=LRDQYOCREKIELY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319166   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biotie Therapies

Curated by ChEMBL

LigandBDBM50319166(1-Propyl-3,4,8-trimethyl-imidazo[1,5-a]pyrido[3,2-...)Copy SMILESCopy InChI

Affinity DataIC50: 8.30nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2010
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