BDBM50319070 (2S,3R,4R,5S,6R)-2-(3-((6-(1,3,4-thiadiazol-2-yl)pyridazin-3-yl)methyl)-4-chlorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1083975::US8541380, 46

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(nn2)-c2nncs2)c1

InChI Key InChIKey=CKAIEVAUHBWSFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319070   

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM50319070(US8541380, 46 | CHEMBL1083975 | (2S,3R,4R,5S,6R)-2...)
Affinity DataIC50: 11.4nMAssay Description:Inhibition assay using hSGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2013
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM50319070(US8541380, 46 | CHEMBL1083975 | (2S,3R,4R,5S,6R)-2...)
Affinity DataIC50: 11.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed