BDBM50319017 4-(5-(2-methoxybenzyl)-3-methylbenzo[b]thiophen-2-yl)pyrimidin-2-amine::CHEMBL1086543

SMILES COc1ccccc1Cc1ccc2sc(c(C)c2c1)-c1ccnc(N)n1

InChI Key InChIKey=WTZGRUBUIGZYJG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319017   

TargetRho-associated protein kinase 1(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319017(4-(5-(2-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of ROCK1 assessed as ATP cunsumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319017(4-(5-(2-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed