BDBM50318674 4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1Hisoindole-5-carbonyl]amino}benzoic Acid::CHEMBL1083969

SMILES OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccccc1O

InChI Key InChIKey=YZCGUQOGRSEYPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318674   

TargetDynamin-1(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed