BDBM50318571 2-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-7-yl)-piperazin-1-yl]-N-thiazol-2-ylacetamide::CHEMBL1086219

SMILES Brc1cnc2nc[nH]c2c1N1CCN(CC(=O)Nc2nccs2)CC1

InChI Key InChIKey=KHNWPAGJZMTRNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318571   

TargetAurora kinase A(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50318571(2-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-7-yl)-piper...)
Affinity DataIC50: 81nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50318571(2-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-7-yl)-piper...)
Affinity DataIC50: 517nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed