BDBM50318491 7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-enyl)heptanoic acid::CHEMBL1084644

SMILES CCCCC[C@H](O)C=C[C@H]1C=CC(=O)[C@@H]1CCCCCCC(O)=O

InChI Key InChIKey=BGKHCLZFGPIKKU-UHFFFAOYSA-N

Data  1 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50318491   

LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  1.51E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Mouse)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Mouse)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Rat)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Rat)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2A1(Rat)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataKi:  286nMAssay Description:TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details
PubMed