BDBM50318426 CHEMBL1094518::N-((S)-3-((3aR,6aS)-5-(2-chloro-4,6-dimethylpyrimidine-5-carbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-1-phenylpropyl)-2-(3,3-difluorocyclobutyl)acetamide

SMILES Cc1nc(Cl)nc(C)c1C(=O)N1C[C@@H]2CN(CC[C@H](NC(=O)CC3CC(F)(F)C3)c3ccccc3)C[C@@H]2C1

InChI Key InChIKey=BHZZWCMIOLBTNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318426   

TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318426(N-((S)-3-((3aR,6aS)-5-(2-chloro-4,6-dimethylpyrimi...)
Affinity DataIC50: 25nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed