BDBM50318376 (Z)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-6-fluoropyridin-2-yl oxime::CHEMBL1098701

SMILES Fc1cccc(O\N=C2\CCCC(=C2)C#Cc2ccccn2)n1

InChI Key InChIKey=MVQLXHSMBRBVJT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318376   

TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50318376((Z)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-6-fl...)
Affinity DataKi:  44.0nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed