BDBM50318312 (R)-5-hexyl-3-phenyloxazolidin-2-one::CHEMBL1094762

SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1

InChI Key InChIKey=VSVXANNIGPUQAD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318312   

TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  450nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  1.38E+4nMAssay Description:Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318312((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Affinity DataEC50:  590nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed