BDBM50318270 CHEMBL1094143::N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide

SMILES O=C(Nc1nc(nc2nn(Cc3ccccc3)cc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=ACNFYYUXBQGWQL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50318270   

TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318270(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 272nMAssay Description:Antagonist activity human recombinant adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated [3H]cAMP accumulation tre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318270(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 53nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318270(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318270(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318270(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed