BDBM50318239 4,4'-((5S,9R)-3-(3,5-Dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7,9-diyl)dibenzonitrile::CHEMBL1096040

SMILES CN1C(=O)N(C(=O)[C@]11CN(C[C@H]1c1ccc(cc1)C#N)c1ccc(cc1)C#N)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=PJQSUTYJMHQWEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318239   

TargetIntegrin alpha-L(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318239(4,4'-((5S,9R)-3-(3,5-Dichlorophenyl)-1-methyl-2,4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed