BDBM50318185 CHEMBL1094782::N-(3-bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES COc1ccc(OC)c(Cc2cc3c(Nc4cccc(Br)c4)ncnc3[nH]2)c1

InChI Key InChIKey=IXGXJNXPVJEGDV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318185   

TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318185(N-(3-bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrro...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of VEGFR2 phosphorylation in human U251 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318185(N-(3-bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrro...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of EGFR phosphorylation in human A431 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318185(N-(3-bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrro...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of VEGFR1 phosphorylation in human A498 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318185(N-(3-bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrro...)
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human SF539 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed