BDBM50318168 CHEMBL1097368::N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES C(Cc1ccccc1)c1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2[nH]1

InChI Key InChIKey=PWLPHODRHOUKAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318168   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 5.61E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed