BDBM50318164 6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL1097743

SMILES FC(F)(F)c1cccc(Nc2ncnc3[nH]c(CCc4ccccc4)cc23)c1

InChI Key InChIKey=PJUIFTJNPUTTFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318164   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318164(6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318164(6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318164(6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H...)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318164(6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed