BDBM50318014 2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-methylpyrimidin-2-yl)benzamide::CHEMBL1094738

SMILES Cc1cnc(nc1)-c1ccc(Cl)c(c1)C(=O)NCC1(O)CCCCCC1

InChI Key InChIKey=DKUSBKIKXOGBSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318014   

TargetP2X purinoceptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318014(2-chloro-N-((1-hydroxycycloheptyl)methyl)-5-(5-met...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed