BDBM50317739 3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097799

SMILES CC(C)c1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=ISMQLWMZRUKHEF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317739   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317739(3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]T0901317 from LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317739(3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human recombinant LXRbeta ligand binding domain in HuH7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50317739(3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8...)
Affinity DataIC50: 8.20nMAssay Description:Displacement of [3H]T0901317 from LXRalpha ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed