BDBM50317560 CHEMBL1095102::N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-8-phenyloctanamide

SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1NC(=O)CCCCCCCc1ccccc1

InChI Key InChIKey=AEXOWBPFMXSRIU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317560   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317560(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-8-ph...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317560(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-8-ph...)
Affinity DataEC50:  2.67E+4nMAssay Description:Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317560(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-8-ph...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed