BDBM50317559 CHEMBL1095101::N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-7-phenylheptanamide

SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1NC(=O)CCCCCCc1ccccc1

InChI Key InChIKey=RNSHNAPUHKCKPJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317559   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317559(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-7-ph...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317559(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-7-ph...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317559(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]-7-ph...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed