BDBM50317557 4-tert-Butyl-N-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]benzamide::CHEMBL1094768

SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1NC(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=PDZNLJVWUYVZLD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317557   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317557(4-tert-Butyl-N-[(1R,2S,5R)-2-isopropyl-5-methylcyc...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317557(4-tert-Butyl-N-[(1R,2S,5R)-2-isopropyl-5-methylcyc...)
Affinity DataIC50: 9.76E+4nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317557(4-tert-Butyl-N-[(1R,2S,5R)-2-isopropyl-5-methylcyc...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as intracellular calcium stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50317557(4-tert-Butyl-N-[(1R,2S,5R)-2-isopropyl-5-methylcyc...)
Affinity DataIC50: 6.08E+4nMAssay Description:Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed