BDBM50317488 (R)-4-(2-((4-(4-(thiophen-3-yl)benzyl)phenoxy)methyl)piperidin-1-yl)butanoic acid::CHEMBL1098532

SMILES OC(=O)CCCN1CCCC[C@@H]1COc1ccc(Cc2ccc(cc2)-c2ccsc2)cc1

InChI Key InChIKey=FQHGCKUMBBZBFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317488   

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50317488((R)-4-(2-((4-(4-(thiophen-3-yl)benzyl)phenoxy)meth...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50317488((R)-4-(2-((4-(4-(thiophen-3-yl)benzyl)phenoxy)meth...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed