BDBM50316857 4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone::CHEMBL1087448

SMILES Oc1ccc(\C=C\C(=O)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)cc1

InChI Key InChIKey=SRDYAWAEKAHCHN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316857   

TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50316857(4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone |...)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50316857(4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone |...)
Affinity DataKi:  1.49E+4nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed