BDBM50316779 2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-phenyl]pentyl}-1H-indole-3-yl}ethanamine hydrochloride::CHEMBL1094835

SMILES COc1ccc(CCOc2ccc3n(CCCCCc4ccc(SC)cc4)cc(CCN)c3c2)cc1

InChI Key InChIKey=GWILIXWGRREEOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316779   

TargetVascular endothelial growth factor receptor 3(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316779(2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316779(2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316779(2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...)
Affinity DataIC50: 980nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316779(2-{5-(4-Methoxyphenethoxy)-1-{5-[4-(methylthio)-ph...)
Affinity DataIC50: 1.45E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed